venofer dosing calculator

Modify Therapy/Monitor Closely. If we don't have the calculator you need then tell us the details and we'll make it for you. Applies only to oral form of both agents. PRECAUTIONS: Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. If either is present, do not use the liquid. Use Caution/Monitor. A: Generally acceptable. Minor/Significance Unknown. Injectafer treatment may be repeated if iron deficiency anemia reoccurs. Minor/Significance Unknown. (3) Known hypersensitivity to Venofer. Anemia; 2015: 763576. For liquid medications, also enter the value of the Medicine Concentration and choose . Minor/Significance Unknown. Then enter the value of the Dosage and choose the unit of measurement from the drop-down menu. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: vitamin products, other iron-containing products. Hypotension following administration of Venofer may be related to rate of administration and/or total dose delivered. [. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or This document does not contain all possible drug interactions. Mean change in Hgb from baseline to Week 5 2,5 Use Caution/Monitor. . Steps on how to print your input & results: 1. Give each dose as 750 mg for a total cumulative dose of 1500 mg of iron per course. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. Applies only to oral form of both agents. 2. famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. iron sucrose, captopril. Copyright 2021 GlobalRPH - Web Development by. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. Anemia; 2015: 763576. Oral and parenteral products - see background option for oral products. 5. Applies only to oral form of both agents. Applies only to oral form of both agents. prescription products. iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. Monitor Closely (1)iron sucrose will decrease the level or effect of sarecycline by inhibition of GI absorption. Properly discard this product when it is expired or no longer needed. This drug is available at a higher level co-pay. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. Iron Product. You may need extra iron because of blood loss during kidney dialysis. The recommended dosage of iron sucrose for repletion of iron deficiency in patients undergoing hemodialysis is 5ml of iron sucrose (100mg of elemental iron) delivered intravenously during the dialysis session. The dosage of iron sucrose is expressed in mg of elemental iron. For patients receiving hemodialysis, administer Feraheme once the blood pressure is stable and the patient has completed at least one hour of hemodialysis. iron sucrose decreases levels of minocycline by inhibition of GI absorption. The dosage of Venofer is expressed in mg of elemental iron. Applies only to oral form of both agents. Nutrition. Get in touch with MDApp by using the following contact details: 2017 - 2023 MDApp. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Serious - Use Alternative (1)iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Separate by 2 hr. sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Use Caution/Monitor. Modify Therapy/Monitor Closely. omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Medscape Education, Improving Quality of Care in Patients With Iron Deficiency Anemia and Inflammatory Bowel Disease, 2010feosol-carbonyl-fe-icar-c-carbonyl-iron-342171Drugs, encoded search term (iron sucrose (Venofer)) and iron sucrose (Venofer), Use of High-Dose Iron in Dialysis in US Tracks PIVOTAL Trial, FDA Watch List Adds Drugs With Anaphylaxis, Herpes, Fetal Death Risk, Dialysis Industry Mergers: Profits Rise as Patient Outcomes Worsen, Hematology-Oncology Guidelines: 2017 Midyear Review. however iron sucrose requires multiple small intermittent doses over days to weeks. Copyright 1993-2021 Iron Sucrose [ Venofer ] Elemental iron: 20 mg/mL (2.5 mL, 5 mL, 10 mL) Solution, Intravenous [preservative free]: [package insert] INDICATIONS: Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD). Applies only to oral form of both agents. Applies only to oral form of both agents. Applies only to oral form of both agents. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Applies only to oral form of both agents. May increase risk of hypotension. Monitor Closely (1)vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Each mL contains 20 mg of elemental iron. All Rights Reserved. provider for the most current information. You are encouraged to report Adverse Drug Events to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. There is in depth information below the form on the method used and on the result provided. Do not double the dose to catch up. Either increases effects of the other by pharmacodynamic synergism. Introduction Uses Dosage Warnings Interactions Stability Introduction Hematinic agent; a polynuclear iron (III)-hydroxide sucrose complex. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. The original formula employs the weight in kg but users can input it in lbs and it gets transformed. 1996 Aug;11(4):139-46. Pediatric Patients (2 Years of Age and Older). If these effects continue or worsen, tell your doctor.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Patients diagnosed with iron deficiency are prescribed iron supplementation, either to replete body stores or to correct anemia. Minor/Significance Unknown. Use Caution/Monitor. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Applies only to oral form of both agents. Consult your pharmacist or local waste disposal company. iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Most Individual plans may vary Applies only to oral form of both agents. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Applies only to oral form of both agents. restrictions. 2. Anaphylaxis may occur with IV iron and resuscitation facilities should be available.11 It would appear that iron polymaltose may have a higher incidence of severe systemic reactions than iron sucrose and ferric carboxymaltose. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. Indicated for treatment of iron deficiency anemia associated with chronic kidney disease, Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week, Non-dialysis-dependent CKD: 200 mg IV injection for 5 doses in over 14 days (cumulative 1000 mg in 14-day period), Peritoneal dialysis-dependent CKD: 300 mg IV infusion (1.5 hr) for 2 doses 14 days apart, THEN 400 mg IV infusion (2.5 hr) 14 days later (cumulative 1000 mg divided in 3 doses/week), Indicated for maintenance treatment of iron-deficient anemia associated with chronic kidney disease, <2 years: Safety and efficacy not established, Iron replacement treatment in pediatric patients has not been established. Applies only to oral form of both agents. Minor/Significance Unknown. The dosage is expressed in terms of mg of elemental iron, with each mL of Feraheme containing 30 mg of elemental iron. Share cases and questions with Physicians on Medscape consult. LBW = Lean body weight in kg. Minor/Significance Unknown. The iron deficit calculator is useful as one of the determinations performed before iron replenishment therapy is initiated. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet. Where C is the concentration of the iron product: Please note that the calculations above are for information purposes only and the individual dose needs to be established by taking into account the current package insert for the elemental iron product used. Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events. Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. After administration of iron dextran complex, evidence of a therapeutic response can be seen in a few days as an increase in the reticulocyte count. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. iron sucrose will decrease the level or effect of omadacycline by inhibition of GI absorption. Use Caution/Monitor. iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Applies only to oral form of both agents. This site contains information for licensed healthcare professionals in the United States. The Ganzoni equation is: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron - carboxymaltose); FERAHEME met the predefined criteria for non-inferiority to Venofer . If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Although anaphylactic reactions known to occur following INFeD administration are usually evident within a few minutes, or sooner, it is recommended that a period of an hour or longer elapse before the remainder of the initial therapeutic dose is given. To view formulary information first create a list of plans. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Observed Hb = the patients current hemoglobin in g/dl. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Monitor Closely (1)iron sucrose decreases levels of deferiprone by enhancing GI absorption. 2010;18(3). Do not mix iron sucrose with other medications or TPN solution. Indications: Ferrlecit is an iron replacement product for treatment of iron deficiency anemia in adult patients and in pediatric patients age 6 years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy. Slow or stop the infusion if adverse reactions occur. Applies only to oral form of both agents. Minor (2)calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. 1) Ganzoni AM. Methods. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. Applies only to oral form of both agents. Venofer treatment may be repeated if necessary. Avoid or Use Alternate Drug. Prescribing and dispensing information For iron sucrose A complex of ferric hydroxide with sucrose containing 2% (20 mg/mL) of iron. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Burns DL, Mascioli EA, Bistrian BR. Use Caution/Monitor. Administer Feraheme as an intravenous infusion in 50-200 mL 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP over at least 15 minutes. Modify Therapy/Monitor Closely. Use Caution/Monitor. Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy.